Name	Flags	Card.	Type	Description & Constraints    Filter: Bindings Constraints Obligations
MedicationStatement		0..*	MedicationStatement	List of Medicines or Supplements taken by the patient
implicitRules	?!Σ	0..1	uri	A set of rules under which this content was created
modifierExtension	?!	0..*	Extension	Extensions that cannot be ignored
status	?!SΣ	1..1	code	Medicine intake status (e.g., active, completed, discontinued) Binding: Medication Status Codes (required): A coded concept indicating the current status of a MedicationStatement.
statusReason		0..*	CodeableConcept	Reason for discontinuation or modification of therapy Binding: SNOMEDCTDrugTherapyStatusCodes (example): A coded concept indicating the reason for the status of the statement.
medication[x]	Σ	1..1	Reference(Medication_Patient)	Medication or supplement taken
subject	Σ	1..1	Reference(Anamnesis_Patient)	Patient taking the medication
Slices for effective[x]	SΣ	1..1		Time interval during which the medication was taken Slice: Unordered, Open by type:$this
effectiveDateTime			dateTime
effectivePeriod			Period
effective[x]:effectivePeriod	Σ	0..1	Period	Period of medication intake
start	SΣC	1..1	dateTime	Start date of medication intake
dosage	S	0..*	Dosage	Details on the dosage of the medication taken
modifierExtension	?!Σ	0..*	Extension	Extensions that cannot be ignored even if unrecognized
timing	SΣ	1..1	Timing	When medication should be administered
modifierExtension	?!Σ	0..*	Extension	Extensions that cannot be ignored even if unrecognized
route	SΣ	1..1	CodeableConcept	How drug should enter body Binding: Dosage direction VS (required)
Documentation for this format

Terminology Bindings

Path	Conformance	ValueSet	URI
MedicationStatement.status	required	Medication Status Codes http://hl7.org/fhir/ValueSet/medication-statement-status|4.0.1 From the FHIR Standard
MedicationStatement.statusReason	example	SNOMEDCTDrugTherapyStatusCodes http://hl7.org/fhir/ValueSet/reason-medication-status-codes From the FHIR Standard
MedicationStatement.dosage.route	required	DOSDIR http://remote-anamnesis.na.icar.cnr/ValueSet/DOSDIR From this IG

Constraints

Id	Grade	Path(s)	Details	Requirements
dom-2	error	MedicationStatement	If the resource is contained in another resource, it SHALL NOT contain nested Resources : contained.contained.empty()
dom-3	error	MedicationStatement	If the resource is contained in another resource, it SHALL be referred to from elsewhere in the resource or SHALL refer to the containing resource : contained.where((('#'+id in (%resource.descendants().reference | %resource.descendants().as(canonical) | %resource.descendants().as(uri) | %resource.descendants().as(url))) or descendants().where(reference = '#').exists() or descendants().where(as(canonical) = '#').exists() or descendants().where(as(canonical) = '#').exists()).not()).trace('unmatched', id).empty()
dom-4	error	MedicationStatement	If a resource is contained in another resource, it SHALL NOT have a meta.versionId or a meta.lastUpdated : contained.meta.versionId.empty() and contained.meta.lastUpdated.empty()
dom-5	error	MedicationStatement	If a resource is contained in another resource, it SHALL NOT have a security label : contained.meta.security.empty()
dom-6	best practice	MedicationStatement	A resource should have narrative for robust management : text.`div`.exists()
ele-1	error	**ALL** elements	All FHIR elements must have a @value or children : hasValue() or (children().count() > id.count())
ext-1	error	**ALL** extensions	Must have either extensions or value[x], not both : extension.exists() != value.exists()

Name	Flags	Card.	Type	Description & Constraints    Filter: Bindings Constraints Obligations
MedicationStatement		0..*	MedicationStatement	List of Medicines or Supplements taken by the patient
status	S	1..1	code	Medicine intake status (e.g., active, completed, discontinued)
statusReason		0..*	CodeableConcept	Reason for discontinuation or modification of therapy
medication[x]		1..1	Reference(Medication_Patient)	Medication or supplement taken
subject		1..1	Reference(Anamnesis_Patient)	Patient taking the medication
Slices for effective[x]	S	1..1	dateTime, Period	Time interval during which the medication was taken Slice: Unordered, Open by type:$this
effective[x]:effectivePeriod		0..1	Period	Period of medication intake
start	S	1..1	dateTime	Start date of medication intake
dosage	S	0..*	Dosage	Details on the dosage of the medication taken
timing	S	1..1	Timing	When medication should be administered
repeat
when		0..*	code	Code for time period of occurrence Binding: EventTiming (required)
route	S	1..1	CodeableConcept	How drug should enter body Binding: Dosage direction VS (required)
Documentation for this format

Terminology Bindings (Differential)

Path	Conformance	ValueSet	URI
MedicationStatement.dosage.timing.repeat.when	required	EventTiming http://hl7.org/fhir/ValueSet/event-timing From the FHIR Standard
MedicationStatement.dosage.route	required	DOSDIR http://remote-anamnesis.na.icar.cnr/ValueSet/DOSDIR From this IG

Name	Flags	Card.	Type	Description & Constraints    Filter: Bindings Constraints Obligations
MedicationStatement		0..*	MedicationStatement	List of Medicines or Supplements taken by the patient
id	Σ	0..1	id	Logical id of this artifact
meta	Σ	0..1	Meta	Metadata about the resource
implicitRules	?!Σ	0..1	uri	A set of rules under which this content was created
language		0..1	code	Language of the resource content Binding: CommonLanguages (preferred): A human language. Additional Bindings Purpose AllLanguages Max Binding
text		0..1	Narrative	Text summary of the resource, for human interpretation This profile does not constrain the narrative in regard to content, language, or traceability to data elements
contained		0..*	Resource	Contained, inline Resources
extension		0..*	Extension	Additional content defined by implementations
modifierExtension	?!	0..*	Extension	Extensions that cannot be ignored
identifier	Σ	0..*	Identifier	External identifier
basedOn	Σ	0..*	Reference(MedicationRequest | CarePlan | ServiceRequest)	Fulfils plan, proposal or order
partOf	Σ	0..*	Reference(MedicationAdministration | MedicationDispense | MedicationStatement | Procedure | Observation)	Part of referenced event
status	?!SΣ	1..1	code	Medicine intake status (e.g., active, completed, discontinued) Binding: Medication Status Codes (required): A coded concept indicating the current status of a MedicationStatement.
statusReason		0..*	CodeableConcept	Reason for discontinuation or modification of therapy Binding: SNOMEDCTDrugTherapyStatusCodes (example): A coded concept indicating the reason for the status of the statement.
category	Σ	0..1	CodeableConcept	Type of medication usage Binding: Medication usage category codes (preferred): A coded concept identifying where the medication included in the MedicationStatement is expected to be consumed or administered.
medication[x]	Σ	1..1	Reference(Medication_Patient)	Medication or supplement taken
subject	Σ	1..1	Reference(Anamnesis_Patient)	Patient taking the medication
context	Σ	0..1	Reference(Encounter | EpisodeOfCare)	Encounter / Episode associated with MedicationStatement
Slices for effective[x]	SΣ	1..1		Time interval during which the medication was taken Slice: Unordered, Open by type:$this
effectiveDateTime			dateTime
effectivePeriod			Period
effective[x]:effectivePeriod	Σ	0..1	Period	Period of medication intake
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations Slice: Unordered, Open by value:url
start	SΣC	1..1	dateTime	Start date of medication intake
end	ΣC	0..1	dateTime	End time with inclusive boundary, if not ongoing
dateAsserted	Σ	0..1	dateTime	When the statement was asserted?
informationSource		0..1	Reference(Patient | Practitioner | PractitionerRole | RelatedPerson | Organization)	Person or organization that provided the information about the taking of this medication
derivedFrom		0..*	Reference(Resource)	Additional supporting information
reasonCode		0..*	CodeableConcept	Reason for why the medication is being/was taken Binding: Condition/Problem/DiagnosisCodes (example): A coded concept identifying why the medication is being taken.
reasonReference		0..*	Reference(Condition | Observation | DiagnosticReport)	Condition or observation that supports why the medication is being/was taken
note		0..*	Annotation	Further information about the statement
dosage	S	0..*	Dosage	Details on the dosage of the medication taken
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations Slice: Unordered, Open by value:url
modifierExtension	?!Σ	0..*	Extension	Extensions that cannot be ignored even if unrecognized
sequence	Σ	0..1	integer	The order of the dosage instructions
text	Σ	0..1	string	Free text dosage instructions e.g. SIG
additionalInstruction	Σ	0..*	CodeableConcept	Supplemental instruction or warnings to the patient - e.g. "with meals", "may cause drowsiness" Binding: SNOMEDCTAdditionalDosageInstructions (example): A coded concept identifying additional instructions such as "take with water" or "avoid operating heavy machinery".
patientInstruction	Σ	0..1	string	Patient or consumer oriented instructions
timing	SΣ	1..1	Timing	When medication should be administered
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations Slice: Unordered, Open by value:url
modifierExtension	?!Σ	0..*	Extension	Extensions that cannot be ignored even if unrecognized
event	Σ	0..*	dateTime	When the event occurs
repeat	ΣC	0..1	Element	When the event is to occur Constraints: tim-1, tim-2, tim-4, tim-5, tim-6, tim-7, tim-8, tim-9, tim-10
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations Slice: Unordered, Open by value:url
bounds[x]	Σ	0..1		Length/Range of lengths, or (Start and/or end) limits
boundsDuration			Duration
boundsRange			Range
boundsPeriod			Period
count	Σ	0..1	positiveInt	Number of times to repeat
countMax	Σ	0..1	positiveInt	Maximum number of times to repeat
duration	Σ	0..1	decimal	How long when it happens
durationMax	Σ	0..1	decimal	How long when it happens (Max)
durationUnit	Σ	0..1	code	s | min | h | d | wk | mo | a - unit of time (UCUM) Binding: UnitsOfTime (required): A unit of time (units from UCUM).
frequency	Σ	0..1	positiveInt	Event occurs frequency times per period
frequencyMax	Σ	0..1	positiveInt	Event occurs up to frequencyMax times per period
period	Σ	0..1	decimal	Event occurs frequency times per period
periodMax	Σ	0..1	decimal	Upper limit of period (3-4 hours)
periodUnit	Σ	0..1	code	s | min | h | d | wk | mo | a - unit of time (UCUM) Binding: UnitsOfTime (required): A unit of time (units from UCUM).
dayOfWeek	Σ	0..*	code	mon | tue | wed | thu | fri | sat | sun Binding: DaysOfWeek (required)
timeOfDay	Σ	0..*	time	Time of day for action
when	Σ	0..*	code	Code for time period of occurrence Binding: EventTiming (required)
offset	Σ	0..1	unsignedInt	Minutes from event (before or after)
code	Σ	0..1	CodeableConcept	BID | TID | QID | AM | PM | QD | QOD | + Binding: TimingAbbreviation (preferred): Code for a known / defined timing pattern.
asNeeded[x]	Σ	0..1		Take "as needed" (for x) Binding: SNOMEDCTMedicationAsNeededReasonCodes (example): A coded concept identifying the precondition that should be met or evaluated prior to consuming or administering a medication dose. For example "pain", "30 minutes prior to sexual intercourse", "on flare-up" etc.
asNeededBoolean			boolean
asNeededCodeableConcept			CodeableConcept
site	Σ	0..1	CodeableConcept	Body site to administer to Binding: SNOMEDCTAnatomicalStructureForAdministrationSiteCodes (example): A coded concept describing the site location the medicine enters into or onto the body.
route	SΣ	1..1	CodeableConcept	How drug should enter body Binding: Dosage direction VS (required)
method	Σ	0..1	CodeableConcept	Technique for administering medication Binding: SNOMEDCTAdministrationMethodCodes (example): A coded concept describing the technique by which the medicine is administered.
doseAndRate	Σ	0..*	Element	Amount of medication administered
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations Slice: Unordered, Open by value:url
type	Σ	0..1	CodeableConcept	The kind of dose or rate specified Binding: DoseAndRateType (example): The kind of dose or rate specified.
dose[x]	Σ	0..1		Amount of medication per dose
doseRange			Range
doseQuantity			Quantity(SimpleQuantity)
rate[x]	Σ	0..1		Amount of medication per unit of time
rateRatio			Ratio
rateRange			Range
rateQuantity			Quantity(SimpleQuantity)
maxDosePerPeriod	Σ	0..1	Ratio	Upper limit on medication per unit of time
maxDosePerAdministration	Σ	0..1	SimpleQuantity	Upper limit on medication per administration
maxDosePerLifetime	Σ	0..1	SimpleQuantity	Upper limit on medication per lifetime of the patient
Documentation for this format

Terminology Bindings

Path	Conformance	ValueSet	URI
MedicationStatement.language	preferred	CommonLanguages http://hl7.org/fhir/ValueSet/languages From the FHIR Standard Additional Bindings Purpose AllLanguages Max Binding
MedicationStatement.status	required	Medication Status Codes http://hl7.org/fhir/ValueSet/medication-statement-status|4.0.1 From the FHIR Standard
MedicationStatement.statusReason	example	SNOMEDCTDrugTherapyStatusCodes http://hl7.org/fhir/ValueSet/reason-medication-status-codes From the FHIR Standard
MedicationStatement.category	preferred	Medication usage category codes http://hl7.org/fhir/ValueSet/medication-statement-category From the FHIR Standard
MedicationStatement.reasonCode	example	Condition/Problem/DiagnosisCodes http://hl7.org/fhir/ValueSet/condition-code From the FHIR Standard
MedicationStatement.dosage.additionalInstruction	example	SNOMEDCTAdditionalDosageInstructions http://hl7.org/fhir/ValueSet/additional-instruction-codes From the FHIR Standard
MedicationStatement.dosage.timing.repeat.durationUnit	required	UnitsOfTime http://hl7.org/fhir/ValueSet/units-of-time|4.0.1 From the FHIR Standard
MedicationStatement.dosage.timing.repeat.periodUnit	required	UnitsOfTime http://hl7.org/fhir/ValueSet/units-of-time|4.0.1 From the FHIR Standard
MedicationStatement.dosage.timing.repeat.dayOfWeek	required	DaysOfWeek http://hl7.org/fhir/ValueSet/days-of-week|4.0.1 From the FHIR Standard
MedicationStatement.dosage.timing.repeat.when	required	EventTiming http://hl7.org/fhir/ValueSet/event-timing From the FHIR Standard
MedicationStatement.dosage.timing.code	preferred	TimingAbbreviation http://hl7.org/fhir/ValueSet/timing-abbreviation From the FHIR Standard
MedicationStatement.dosage.asNeeded[x]	example	SNOMEDCTMedicationAsNeededReasonCodes http://hl7.org/fhir/ValueSet/medication-as-needed-reason From the FHIR Standard
MedicationStatement.dosage.site	example	SNOMEDCTAnatomicalStructureForAdministrationSiteCodes http://hl7.org/fhir/ValueSet/approach-site-codes From the FHIR Standard
MedicationStatement.dosage.route	required	DOSDIR http://remote-anamnesis.na.icar.cnr/ValueSet/DOSDIR From this IG
MedicationStatement.dosage.method	example	SNOMEDCTAdministrationMethodCodes http://hl7.org/fhir/ValueSet/administration-method-codes From the FHIR Standard
MedicationStatement.dosage.doseAndRate.type	example	DoseAndRateType http://hl7.org/fhir/ValueSet/dose-rate-type From the FHIR Standard

Constraints

Id	Grade	Path(s)	Details	Requirements
dom-2	error	MedicationStatement	If the resource is contained in another resource, it SHALL NOT contain nested Resources : contained.contained.empty()
dom-3	error	MedicationStatement	If the resource is contained in another resource, it SHALL be referred to from elsewhere in the resource or SHALL refer to the containing resource : contained.where((('#'+id in (%resource.descendants().reference | %resource.descendants().as(canonical) | %resource.descendants().as(uri) | %resource.descendants().as(url))) or descendants().where(reference = '#').exists() or descendants().where(as(canonical) = '#').exists() or descendants().where(as(canonical) = '#').exists()).not()).trace('unmatched', id).empty()
dom-4	error	MedicationStatement	If a resource is contained in another resource, it SHALL NOT have a meta.versionId or a meta.lastUpdated : contained.meta.versionId.empty() and contained.meta.lastUpdated.empty()
dom-5	error	MedicationStatement	If a resource is contained in another resource, it SHALL NOT have a security label : contained.meta.security.empty()
dom-6	best practice	MedicationStatement	A resource should have narrative for robust management : text.`div`.exists()
ele-1	error	**ALL** elements	All FHIR elements must have a @value or children : hasValue() or (children().count() > id.count())
ext-1	error	**ALL** extensions	Must have either extensions or value[x], not both : extension.exists() != value.exists()
tim-1	error	MedicationStatement.dosage.timing.repeat	if there's a duration, there needs to be duration units : duration.empty() or durationUnit.exists()
tim-2	error	MedicationStatement.dosage.timing.repeat	if there's a period, there needs to be period units : period.empty() or periodUnit.exists()
tim-4	error	MedicationStatement.dosage.timing.repeat	duration SHALL be a non-negative value : duration.exists() implies duration >= 0
tim-5	error	MedicationStatement.dosage.timing.repeat	period SHALL be a non-negative value : period.exists() implies period >= 0
tim-6	error	MedicationStatement.dosage.timing.repeat	If there's a periodMax, there must be a period : periodMax.empty() or period.exists()
tim-7	error	MedicationStatement.dosage.timing.repeat	If there's a durationMax, there must be a duration : durationMax.empty() or duration.exists()
tim-8	error	MedicationStatement.dosage.timing.repeat	If there's a countMax, there must be a count : countMax.empty() or count.exists()
tim-9	error	MedicationStatement.dosage.timing.repeat	If there's an offset, there must be a when (and not C, CM, CD, CV) : offset.empty() or (when.exists() and ((when in ('C' | 'CM' | 'CD' | 'CV')).not()))
tim-10	error	MedicationStatement.dosage.timing.repeat	If there's a timeOfDay, there cannot be a when, or vice versa : timeOfDay.empty() or when.empty()

Summary

Mandatory: 1 element(3 nested mandatory elements)
Must-Support: 6 elements

Structures

This structure refers to these other structures:

• Medication_Patient (http://remote-anamnesis.na.icar.cnr/StructureDefinition/medication-patient)
• Anamnesis_Patient (http://remote-anamnesis.na.icar.cnr/StructureDefinition/patient-anamnesi)

Slices

This structure defines the following Slices:

• The element 1 is sliced based on the value of MedicationStatement.effective[x]

Name	Flags	Card.	Type	Description & Constraints    Filter: Bindings Constraints Obligations
MedicationStatement		0..*	MedicationStatement	List of Medicines or Supplements taken by the patient
implicitRules	?!Σ	0..1	uri	A set of rules under which this content was created
modifierExtension	?!	0..*	Extension	Extensions that cannot be ignored
status	?!SΣ	1..1	code	Medicine intake status (e.g., active, completed, discontinued) Binding: Medication Status Codes (required): A coded concept indicating the current status of a MedicationStatement.
statusReason		0..*	CodeableConcept	Reason for discontinuation or modification of therapy Binding: SNOMEDCTDrugTherapyStatusCodes (example): A coded concept indicating the reason for the status of the statement.
medication[x]	Σ	1..1	Reference(Medication_Patient)	Medication or supplement taken
subject	Σ	1..1	Reference(Anamnesis_Patient)	Patient taking the medication
Slices for effective[x]	SΣ	1..1		Time interval during which the medication was taken Slice: Unordered, Open by type:$this
effectiveDateTime			dateTime
effectivePeriod			Period
effective[x]:effectivePeriod	Σ	0..1	Period	Period of medication intake
start	SΣC	1..1	dateTime	Start date of medication intake
dosage	S	0..*	Dosage	Details on the dosage of the medication taken
modifierExtension	?!Σ	0..*	Extension	Extensions that cannot be ignored even if unrecognized
timing	SΣ	1..1	Timing	When medication should be administered
modifierExtension	?!Σ	0..*	Extension	Extensions that cannot be ignored even if unrecognized
route	SΣ	1..1	CodeableConcept	How drug should enter body Binding: Dosage direction VS (required)
Documentation for this format

Terminology Bindings

Path	Conformance	ValueSet	URI
MedicationStatement.status	required	Medication Status Codes http://hl7.org/fhir/ValueSet/medication-statement-status|4.0.1 From the FHIR Standard
MedicationStatement.statusReason	example	SNOMEDCTDrugTherapyStatusCodes http://hl7.org/fhir/ValueSet/reason-medication-status-codes From the FHIR Standard
MedicationStatement.dosage.route	required	DOSDIR http://remote-anamnesis.na.icar.cnr/ValueSet/DOSDIR From this IG

Constraints

Id	Grade	Path(s)	Details	Requirements
dom-2	error	MedicationStatement	If the resource is contained in another resource, it SHALL NOT contain nested Resources : contained.contained.empty()
dom-3	error	MedicationStatement	If the resource is contained in another resource, it SHALL be referred to from elsewhere in the resource or SHALL refer to the containing resource : contained.where((('#'+id in (%resource.descendants().reference | %resource.descendants().as(canonical) | %resource.descendants().as(uri) | %resource.descendants().as(url))) or descendants().where(reference = '#').exists() or descendants().where(as(canonical) = '#').exists() or descendants().where(as(canonical) = '#').exists()).not()).trace('unmatched', id).empty()
dom-4	error	MedicationStatement	If a resource is contained in another resource, it SHALL NOT have a meta.versionId or a meta.lastUpdated : contained.meta.versionId.empty() and contained.meta.lastUpdated.empty()
dom-5	error	MedicationStatement	If a resource is contained in another resource, it SHALL NOT have a security label : contained.meta.security.empty()
dom-6	best practice	MedicationStatement	A resource should have narrative for robust management : text.`div`.exists()
ele-1	error	**ALL** elements	All FHIR elements must have a @value or children : hasValue() or (children().count() > id.count())
ext-1	error	**ALL** extensions	Must have either extensions or value[x], not both : extension.exists() != value.exists()

Name	Flags	Card.	Type	Description & Constraints    Filter: Bindings Constraints Obligations
MedicationStatement		0..*	MedicationStatement	List of Medicines or Supplements taken by the patient
status	S	1..1	code	Medicine intake status (e.g., active, completed, discontinued)
statusReason		0..*	CodeableConcept	Reason for discontinuation or modification of therapy
medication[x]		1..1	Reference(Medication_Patient)	Medication or supplement taken
subject		1..1	Reference(Anamnesis_Patient)	Patient taking the medication
Slices for effective[x]	S	1..1	dateTime, Period	Time interval during which the medication was taken Slice: Unordered, Open by type:$this
effective[x]:effectivePeriod		0..1	Period	Period of medication intake
start	S	1..1	dateTime	Start date of medication intake
dosage	S	0..*	Dosage	Details on the dosage of the medication taken
timing	S	1..1	Timing	When medication should be administered
repeat
when		0..*	code	Code for time period of occurrence Binding: EventTiming (required)
route	S	1..1	CodeableConcept	How drug should enter body Binding: Dosage direction VS (required)
Documentation for this format

Terminology Bindings (Differential)

Path	Conformance	ValueSet	URI
MedicationStatement.dosage.timing.repeat.when	required	EventTiming http://hl7.org/fhir/ValueSet/event-timing From the FHIR Standard
MedicationStatement.dosage.route	required	DOSDIR http://remote-anamnesis.na.icar.cnr/ValueSet/DOSDIR From this IG

Name	Flags	Card.	Type	Description & Constraints    Filter: Bindings Constraints Obligations
MedicationStatement		0..*	MedicationStatement	List of Medicines or Supplements taken by the patient
id	Σ	0..1	id	Logical id of this artifact
meta	Σ	0..1	Meta	Metadata about the resource
implicitRules	?!Σ	0..1	uri	A set of rules under which this content was created
language		0..1	code	Language of the resource content Binding: CommonLanguages (preferred): A human language. Additional Bindings Purpose AllLanguages Max Binding
text		0..1	Narrative	Text summary of the resource, for human interpretation This profile does not constrain the narrative in regard to content, language, or traceability to data elements
contained		0..*	Resource	Contained, inline Resources
extension		0..*	Extension	Additional content defined by implementations
modifierExtension	?!	0..*	Extension	Extensions that cannot be ignored
identifier	Σ	0..*	Identifier	External identifier
basedOn	Σ	0..*	Reference(MedicationRequest | CarePlan | ServiceRequest)	Fulfils plan, proposal or order
partOf	Σ	0..*	Reference(MedicationAdministration | MedicationDispense | MedicationStatement | Procedure | Observation)	Part of referenced event
status	?!SΣ	1..1	code	Medicine intake status (e.g., active, completed, discontinued) Binding: Medication Status Codes (required): A coded concept indicating the current status of a MedicationStatement.
statusReason		0..*	CodeableConcept	Reason for discontinuation or modification of therapy Binding: SNOMEDCTDrugTherapyStatusCodes (example): A coded concept indicating the reason for the status of the statement.
category	Σ	0..1	CodeableConcept	Type of medication usage Binding: Medication usage category codes (preferred): A coded concept identifying where the medication included in the MedicationStatement is expected to be consumed or administered.
medication[x]	Σ	1..1	Reference(Medication_Patient)	Medication or supplement taken
subject	Σ	1..1	Reference(Anamnesis_Patient)	Patient taking the medication
context	Σ	0..1	Reference(Encounter | EpisodeOfCare)	Encounter / Episode associated with MedicationStatement
Slices for effective[x]	SΣ	1..1		Time interval during which the medication was taken Slice: Unordered, Open by type:$this
effectiveDateTime			dateTime
effectivePeriod			Period
effective[x]:effectivePeriod	Σ	0..1	Period	Period of medication intake
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations Slice: Unordered, Open by value:url
start	SΣC	1..1	dateTime	Start date of medication intake
end	ΣC	0..1	dateTime	End time with inclusive boundary, if not ongoing
dateAsserted	Σ	0..1	dateTime	When the statement was asserted?
informationSource		0..1	Reference(Patient | Practitioner | PractitionerRole | RelatedPerson | Organization)	Person or organization that provided the information about the taking of this medication
derivedFrom		0..*	Reference(Resource)	Additional supporting information
reasonCode		0..*	CodeableConcept	Reason for why the medication is being/was taken Binding: Condition/Problem/DiagnosisCodes (example): A coded concept identifying why the medication is being taken.
reasonReference		0..*	Reference(Condition | Observation | DiagnosticReport)	Condition or observation that supports why the medication is being/was taken
note		0..*	Annotation	Further information about the statement
dosage	S	0..*	Dosage	Details on the dosage of the medication taken
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations Slice: Unordered, Open by value:url
modifierExtension	?!Σ	0..*	Extension	Extensions that cannot be ignored even if unrecognized
sequence	Σ	0..1	integer	The order of the dosage instructions
text	Σ	0..1	string	Free text dosage instructions e.g. SIG
additionalInstruction	Σ	0..*	CodeableConcept	Supplemental instruction or warnings to the patient - e.g. "with meals", "may cause drowsiness" Binding: SNOMEDCTAdditionalDosageInstructions (example): A coded concept identifying additional instructions such as "take with water" or "avoid operating heavy machinery".
patientInstruction	Σ	0..1	string	Patient or consumer oriented instructions
timing	SΣ	1..1	Timing	When medication should be administered
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations Slice: Unordered, Open by value:url
modifierExtension	?!Σ	0..*	Extension	Extensions that cannot be ignored even if unrecognized
event	Σ	0..*	dateTime	When the event occurs
repeat	ΣC	0..1	Element	When the event is to occur Constraints: tim-1, tim-2, tim-4, tim-5, tim-6, tim-7, tim-8, tim-9, tim-10
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations Slice: Unordered, Open by value:url
bounds[x]	Σ	0..1		Length/Range of lengths, or (Start and/or end) limits
boundsDuration			Duration
boundsRange			Range
boundsPeriod			Period
count	Σ	0..1	positiveInt	Number of times to repeat
countMax	Σ	0..1	positiveInt	Maximum number of times to repeat
duration	Σ	0..1	decimal	How long when it happens
durationMax	Σ	0..1	decimal	How long when it happens (Max)
durationUnit	Σ	0..1	code	s | min | h | d | wk | mo | a - unit of time (UCUM) Binding: UnitsOfTime (required): A unit of time (units from UCUM).
frequency	Σ	0..1	positiveInt	Event occurs frequency times per period
frequencyMax	Σ	0..1	positiveInt	Event occurs up to frequencyMax times per period
period	Σ	0..1	decimal	Event occurs frequency times per period
periodMax	Σ	0..1	decimal	Upper limit of period (3-4 hours)
periodUnit	Σ	0..1	code	s | min | h | d | wk | mo | a - unit of time (UCUM) Binding: UnitsOfTime (required): A unit of time (units from UCUM).
dayOfWeek	Σ	0..*	code	mon | tue | wed | thu | fri | sat | sun Binding: DaysOfWeek (required)
timeOfDay	Σ	0..*	time	Time of day for action
when	Σ	0..*	code	Code for time period of occurrence Binding: EventTiming (required)
offset	Σ	0..1	unsignedInt	Minutes from event (before or after)
code	Σ	0..1	CodeableConcept	BID | TID | QID | AM | PM | QD | QOD | + Binding: TimingAbbreviation (preferred): Code for a known / defined timing pattern.
asNeeded[x]	Σ	0..1		Take "as needed" (for x) Binding: SNOMEDCTMedicationAsNeededReasonCodes (example): A coded concept identifying the precondition that should be met or evaluated prior to consuming or administering a medication dose. For example "pain", "30 minutes prior to sexual intercourse", "on flare-up" etc.
asNeededBoolean			boolean
asNeededCodeableConcept			CodeableConcept
site	Σ	0..1	CodeableConcept	Body site to administer to Binding: SNOMEDCTAnatomicalStructureForAdministrationSiteCodes (example): A coded concept describing the site location the medicine enters into or onto the body.
route	SΣ	1..1	CodeableConcept	How drug should enter body Binding: Dosage direction VS (required)
method	Σ	0..1	CodeableConcept	Technique for administering medication Binding: SNOMEDCTAdministrationMethodCodes (example): A coded concept describing the technique by which the medicine is administered.
doseAndRate	Σ	0..*	Element	Amount of medication administered
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations Slice: Unordered, Open by value:url
type	Σ	0..1	CodeableConcept	The kind of dose or rate specified Binding: DoseAndRateType (example): The kind of dose or rate specified.
dose[x]	Σ	0..1		Amount of medication per dose
doseRange			Range
doseQuantity			Quantity(SimpleQuantity)
rate[x]	Σ	0..1		Amount of medication per unit of time
rateRatio			Ratio
rateRange			Range
rateQuantity			Quantity(SimpleQuantity)
maxDosePerPeriod	Σ	0..1	Ratio	Upper limit on medication per unit of time
maxDosePerAdministration	Σ	0..1	SimpleQuantity	Upper limit on medication per administration
maxDosePerLifetime	Σ	0..1	SimpleQuantity	Upper limit on medication per lifetime of the patient
Documentation for this format

Terminology Bindings

Path	Conformance	ValueSet	URI
MedicationStatement.language	preferred	CommonLanguages http://hl7.org/fhir/ValueSet/languages From the FHIR Standard Additional Bindings Purpose AllLanguages Max Binding
MedicationStatement.status	required	Medication Status Codes http://hl7.org/fhir/ValueSet/medication-statement-status|4.0.1 From the FHIR Standard
MedicationStatement.statusReason	example	SNOMEDCTDrugTherapyStatusCodes http://hl7.org/fhir/ValueSet/reason-medication-status-codes From the FHIR Standard
MedicationStatement.category	preferred	Medication usage category codes http://hl7.org/fhir/ValueSet/medication-statement-category From the FHIR Standard
MedicationStatement.reasonCode	example	Condition/Problem/DiagnosisCodes http://hl7.org/fhir/ValueSet/condition-code From the FHIR Standard
MedicationStatement.dosage.additionalInstruction	example	SNOMEDCTAdditionalDosageInstructions http://hl7.org/fhir/ValueSet/additional-instruction-codes From the FHIR Standard
MedicationStatement.dosage.timing.repeat.durationUnit	required	UnitsOfTime http://hl7.org/fhir/ValueSet/units-of-time|4.0.1 From the FHIR Standard
MedicationStatement.dosage.timing.repeat.periodUnit	required	UnitsOfTime http://hl7.org/fhir/ValueSet/units-of-time|4.0.1 From the FHIR Standard
MedicationStatement.dosage.timing.repeat.dayOfWeek	required	DaysOfWeek http://hl7.org/fhir/ValueSet/days-of-week|4.0.1 From the FHIR Standard
MedicationStatement.dosage.timing.repeat.when	required	EventTiming http://hl7.org/fhir/ValueSet/event-timing From the FHIR Standard
MedicationStatement.dosage.timing.code	preferred	TimingAbbreviation http://hl7.org/fhir/ValueSet/timing-abbreviation From the FHIR Standard
MedicationStatement.dosage.asNeeded[x]	example	SNOMEDCTMedicationAsNeededReasonCodes http://hl7.org/fhir/ValueSet/medication-as-needed-reason From the FHIR Standard
MedicationStatement.dosage.site	example	SNOMEDCTAnatomicalStructureForAdministrationSiteCodes http://hl7.org/fhir/ValueSet/approach-site-codes From the FHIR Standard
MedicationStatement.dosage.route	required	DOSDIR http://remote-anamnesis.na.icar.cnr/ValueSet/DOSDIR From this IG
MedicationStatement.dosage.method	example	SNOMEDCTAdministrationMethodCodes http://hl7.org/fhir/ValueSet/administration-method-codes From the FHIR Standard
MedicationStatement.dosage.doseAndRate.type	example	DoseAndRateType http://hl7.org/fhir/ValueSet/dose-rate-type From the FHIR Standard

Constraints

Id	Grade	Path(s)	Details	Requirements
dom-2	error	MedicationStatement	If the resource is contained in another resource, it SHALL NOT contain nested Resources : contained.contained.empty()
dom-3	error	MedicationStatement	If the resource is contained in another resource, it SHALL be referred to from elsewhere in the resource or SHALL refer to the containing resource : contained.where((('#'+id in (%resource.descendants().reference | %resource.descendants().as(canonical) | %resource.descendants().as(uri) | %resource.descendants().as(url))) or descendants().where(reference = '#').exists() or descendants().where(as(canonical) = '#').exists() or descendants().where(as(canonical) = '#').exists()).not()).trace('unmatched', id).empty()
dom-4	error	MedicationStatement	If a resource is contained in another resource, it SHALL NOT have a meta.versionId or a meta.lastUpdated : contained.meta.versionId.empty() and contained.meta.lastUpdated.empty()
dom-5	error	MedicationStatement	If a resource is contained in another resource, it SHALL NOT have a security label : contained.meta.security.empty()
dom-6	best practice	MedicationStatement	A resource should have narrative for robust management : text.`div`.exists()
ele-1	error	**ALL** elements	All FHIR elements must have a @value or children : hasValue() or (children().count() > id.count())
ext-1	error	**ALL** extensions	Must have either extensions or value[x], not both : extension.exists() != value.exists()
tim-1	error	MedicationStatement.dosage.timing.repeat	if there's a duration, there needs to be duration units : duration.empty() or durationUnit.exists()
tim-2	error	MedicationStatement.dosage.timing.repeat	if there's a period, there needs to be period units : period.empty() or periodUnit.exists()
tim-4	error	MedicationStatement.dosage.timing.repeat	duration SHALL be a non-negative value : duration.exists() implies duration >= 0
tim-5	error	MedicationStatement.dosage.timing.repeat	period SHALL be a non-negative value : period.exists() implies period >= 0
tim-6	error	MedicationStatement.dosage.timing.repeat	If there's a periodMax, there must be a period : periodMax.empty() or period.exists()
tim-7	error	MedicationStatement.dosage.timing.repeat	If there's a durationMax, there must be a duration : durationMax.empty() or duration.exists()
tim-8	error	MedicationStatement.dosage.timing.repeat	If there's a countMax, there must be a count : countMax.empty() or count.exists()
tim-9	error	MedicationStatement.dosage.timing.repeat	If there's an offset, there must be a when (and not C, CM, CD, CV) : offset.empty() or (when.exists() and ((when in ('C' | 'CM' | 'CD' | 'CV')).not()))
tim-10	error	MedicationStatement.dosage.timing.repeat	If there's a timeOfDay, there cannot be a when, or vice versa : timeOfDay.empty() or when.empty()

Summary

Mandatory: 1 element(3 nested mandatory elements)
Must-Support: 6 elements

Structures

This structure refers to these other structures:

• Medication_Patient (http://remote-anamnesis.na.icar.cnr/StructureDefinition/medication-patient)
• Anamnesis_Patient (http://remote-anamnesis.na.icar.cnr/StructureDefinition/patient-anamnesi)

Slices

This structure defines the following Slices:

• The element 1 is sliced based on the value of MedicationStatement.effective[x]